Assessing the risk of DIC development in sepsis and SIRS

Our model provides a clinically applicable method to identify sepsis/SIRS patients with a high probability to develop DIC well in advance

Real-world data on the effect of anticoagulants to prevent or treat DIC

Our results indicate that anticoagulant treatment may benefit septic patients in terms of DIC development and outcome. This effect seems to be strongly dependent on the timing and duration of the anticoagulant treatment. Further (prospective, interventional) research studies are needed to substantiate our early findings.